After a year I finally got a diagnosis, albeit not one I really wanted to hear. Bladder cancer. The first urologist I had really gave me the run around with tests and procedures, and after 8 months never found the problem. Long story there. I got a second opinion and after he saw the medications weren't working, did a urine cytology test that came back positive. He then did a Cystoscopy with biopsy that confirmed bladder cancer. It appears to be confined to the inner wall of the bladder but he said it was everywhere on the inner bladder wall. I'm now doing Mitomyacin bladder infusions and have completed 3 of 6 treatments and will be re-evaluated a month after treatment #6. I'm a 58 year old man that has work in the trucking-gas and oil industry all my life. I guess it caught up to me.