that's an excellent question. I am also not a medical professional, just a nerdy caregiver who reads a lot in moments of stress. What I learned about bladder cancer is that it doesn't "move through stages" inasmuch as we use those stages to describe the bladder cancer doctors observe. Once we observe certain behaviors, markers, etc, we then describe it as a different stage in our understanding. Certain rare cancers can also act in ways that are far different from "lower grade" cancers. I think your question was awesome, and I hope this helps! All my best, Charles (Moderator / BladderCancer.net)