Intravesical Mitomycin C - After It's in There
I'm having a course of six weekly treatments with intravesical mMitomycin C. There seems no consistent advice on what to do immediately after having the Mitomycin C put in the bladder.
Some advice says the Mitomycin C should stay in the bladder for 1 hour, others say 1-2 hours.
One website states "You may need to change positions every 15 minutes to be sure the drug reaches all areas of the bladder. Do this by rolling on your side, back, other side and stomach." I asked my specialist nurse and she suggested just going up and down stairs would be good. Others give no advice at all.
The suggestions on putting bleach down the toilet after you pee to destroy the mitomycin are variable, ranging from two cupfuls after every time you pee for the next 6 hours to 50ml, others omit that and say flush twice after you pee.
I've a feeling there is little evidence of efficacy for much, if any, of the advice on this. Most seems to be what the medical profession guesses might be best.
The advice I feel most inclined to follow is found here:
https://www.oncolink.org/cancer-treatment/oncolink-rx/intravesicular-mitomycin-mutamycin-r-mitomycin-c-given-into-the-bladder.
What does anyone else think?
I would like to see a consensus on this from the medical profession. Have there been any discussions around this?
Re: changing positions etc, is there any evidence that tumours recur anywhere in particular on the bladder wall following intravesical therapy, either with Mitomycin C or BCG?
Jeff, this may help. I have been offered a course of "hot" Intravesical Mitomycin C in which the fluid is pumped through the bladder and through a heater for an hour or so. Apparently I will have to recline in one position throughout (they suggested taking a book). When they say "hot" it is apparently not uncomfortably so. You could enquire about that (at least it would make your first two questions unnecessary).
